Ramos said he suffered the injury while on international duty with Spain
Real Madrid captain Sergio Ramos is set to miss both legs of the Champions League quarter-final against Liverpool after suffering a calf muscle injury.
The 35-year-old defender picked up the injury while on international duty.
Real face the Reds on Tuesday, 6 April and Wednesday, 14 April, either side of El Clasico with Barcelona in La Liga.
“If there is something that hurts me, it is not being able to help the team in these highly demanding matches,” said the Spaniard on Instagram.
Real are at home for the first leg against Liverpool.