Paris St-Germain have ruled Neymar out of the second leg of their last-16 Champions League tie against Barcelona.
The Brazil forward missed the first leg against his former side, which PSG won 4-1, with a thigh injury.
“Neymar returned to partial training with the squad last week and will continue to work back to fitness individually,” said a PSG statement.
Barcelona will be without defenders Gerard Pique and Ronald Araujo for the match in Paris on Wednesday.
Pique sustained a knee injury in the Copa del Rey semi-final win over Sevilla on 3 March, while Araujo has returned to training after an ankle problem but is not in the squad.
Ex-Liverpool midfielder Philippe Coutinho is still missing for the Spanish side because of a knee injury.
Barcelona, who lost 8-2 to eventual winners Bayern Munich in last season’s one-legged quarter-final, have made it past the last 16 of the Champions League in each of the past 13 seasons.
In 2016-17, they were beaten 4-0 by PSG in the last-16 first leg in Paris, before winning the second leg 6-1 in Spain.
Barcelona head coach Ronald Koeman remained optimistic his side could reach the quarter-finals and said: “It is always different to have a result like this.
“Losing 4-1 at home means we have to score goals away from home and it’s more complicated but nothing is impossible.
“We believe in ourselves – we know we are Barca and have to win and will demonstrate this mentality.”
PSG boss Mauricio Pochettino, who took Tottenham to the Champions League final in 2018-19, will also be without on-loan Everton striker Moise Kean as he is self-isolating because of coronavirus.
Neymar helped the French champions reach their first Champions League final last August and has scored 12 goals in 17 competitive fixtures this season.