A 59-year-old man in Mexico has died with a type of bird flu – H5N2 – never recorded in people before now.
There is no risk to the wider public, say authorities, and none of the man’s close contacts have caught the virus.
It is unclear how he got it, although there have been cases in some poultry farms in Mexico.
Infections like this can sometime pass from animals to humans.
The man had other underlying health issues that likely made him vulnerable.
He had been bedridden for weeks before getting sick with fever and shortness of breath from bird flu, according to officials.
There is no evidence that the virus could start spreading between people and cause an outbreak, they say.
The World Health Organization and other authorities monitor strains of flu, like this one, that could have the potential mutate and become a threat.